The authors of the study noted that moderate coffee consumption has been inversely associated with mortality. However, they asked, does heavy intake, particularly among those with common genetic polymorphisms that impair caffeine metabolism, increase risk of mortality?
They found inverse associations for coffee drinking with mortality, including among participants drinking one up to eight or more cups per day.
No differences were observed in analyses that were stratified by genetic polymorphisms affecting caffeine metabolism.
“This study provides further evidence that coffee drinking can be part of a healthy diet and offers reassurance to coffee drinkers,” the authors of the study said.
“These findings suggest the importance of non-caffeine constituents in the coffee-mortality association and provide further reassurance that coffee drinking can be a part of a healthy diet,” they concluded.